Analogy Assembling of a System for Continuous Monitoring of Biological Samples 

Contact:

Casper H. Clausen, Post Doc, cahu@nanotech.dtu.dk

The aim of this project is to develop a system, which will be able to obtain information about cell topology, both single cells and clusters of cells, after triggering particular signaling e.g. metabolic pathways provided by the application of real-time cellular imaging system scanned from outside of cells. The system will be able to apply a combination of optical, electrical, and mechanical signals to the cell(s) in question as well as readout the cell(s) response with the same techniques.

The goal of this project is to use the principle of SPM for the mechanical stimulation and readout and multi array electrodes for the electrical measurements. Both techniques are each well developed, which would allow for easy combination. Further, a fluidic system will be made in order for the samples to be in a physiological environment. You will learn to design and assembly of setups as well as theory and possibilities behind SPM.